From our guides: What Is 7-OH? How It Is Sold, Why It Matters and Where to Get Help
October 29, 2026 · 0:11
What 7-OH (7-hydroxymitragynine) is, how concentrated 7-OH products are sold, why the FDA calls it an opioid, where federal and South Carolina law stand, and how buprenorphine-based treatment can help with 7-OH dependence.
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Frequently Asked Questions
No. The FDA says there are no FDA-approved 7-OH drugs, 7-OH is not lawful in dietary supplements, and 7-OH cannot be lawfully added to conventional foods.
A 2021 review in the Journal of Addiction Medicine noted that there were no guidelines for treating opioid use disorder stemming from kratom use. It combined a small case series with a literature review of patients treated with buprenorphine-naloxone. Your provider can talk with you about whether buprenorphine fits your situation.
South Carolina's kratom law, Act 35, requires a clear label listing the ingredients, the amount of mitragynine and 7-OH, the serving size and servings per container, the vendor's name and address, any precautionary statements, a statement that the product is not intended to diagnose, treat, cure or prevent any disease, and a statement that sales to anyone under 21 are prohibited.
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