7-OH West Ashley Charleston SC - What It Is and Why It Matters | Hope Integrative Medicine
October 26, 2026 · 1:20
What 7-OH (7-hydroxymitragynine) is, how concentrated 7-OH products are sold, why the FDA calls it an opioid, where federal and South Carolina law stand, and how buprenorphine-based treatment can help with 7-OH dependence.
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Transcript
What is 7-OH? Here is what it is, how it is sold, why it matters, and where to get help. 7-OH is short for 7-hydroxymitragynine. It occurs naturally in only trace amounts in the kratom plant. The products the FDA warns about contain concentrated 7-OH. Concentrated 7-OH is sold as tablets, gummies, drink mixes and shots. The FDA says it is readily available online and at smoke shops, gas stations and corner stores. 7-OH binds to opioid receptors. In 2025, the FDA commissioner called it an opioid that can be more potent than morphine. Regular use can lead to cravings, dependence and withdrawal when you stop. Having trouble stopping? Treatment is available. Doctors have used buprenorphine for kratom dependence in published case reports, though no formal guidelines exist yet. Hope Integrative Medicine offers it in West Ashley and by telehealth across South Carolina. Read the full guide at hopeintegrativemed.com. If someone is very drowsy, hard to wake or breathing slowly, call 911 and give naloxone.
Frequently Asked Questions
The FDA says 7-OH is a naturally occurring alkaloid in the kratom plant but only a minor one, less than 2% of the total alkaloid content in natural kratom leaves. It shows substantially greater mu-opioid receptor potency than mitragynine, kratom's main alkaloid, and than classical opioids such as morphine.
As of October 2026, not yet. On October 14, 2026, the DEA published a notice of intent to temporarily place 7-OH in Schedule I when a product is above a specified threshold, such as more than 1 milligram per gram in solid products or 1 milligram per milliliter in liquids. The notice says the order will be published on or after November 13, 2026. Check current federal law.
The FDA lists withdrawal symptoms such as restlessness, body aches, fatigue, irritability and cold sweats. If you are having trouble stopping 7-OH, talk with a clinician; the FDA notes there are approved treatments for opioid addiction.
