Non-Stimulant ADHD Medicine: What Adults Should Know
Based on Supernus Pharmaceuticals, FDA Approval of Qelbree for the Treatment of ADHD in Adults
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How atomoxetine (Strattera) and viloxazine (Qelbree) work, how long they take, their side effects, and who is a good candidate for a non-stimulant.
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In this guide
Strattera at a Glance
- Atomoxetine, approved for adults
- Full effect in four to eight weeks
- May cause nausea or lower appetite
Qelbree at a Glance
- Viloxazine, approved for adults in 2022
- May help within a few weeks
- Share your full medication list
Before You Start
- Heart review for every ADHD medicine
- Report any worsening mood
- Ask about other options
What the guideline says
- Non-stimulant ADHD medications are effective, are not controlled substances, and work around the clock once they take effect.
- Atomoxetine (Strattera) is a norepinephrine reuptake inhibitor approved for adult ADHD that builds up over four to eight weeks, so patience matters.
- Viloxazine (Qelbree) was approved for adults in 2022 and may start helping within a few weeks.
- Good candidates for a non-stimulant include adults with anxiety that stimulants worsen, a history of substance use, or a preference for a non-controlled option.
- Atomoxetine and viloxazine can raise heart rate and blood pressure, so every ADHD medicine, stimulant or not, needs a heart review first.
Source: Supernus Pharmaceuticals, FDA Approval of Qelbree for the Treatment of ADHD in Adults
Read the full article: Strattera and Qelbree: Non-Stimulant ADHD Medications for Adults →
This guide is general health information and does not replace advice from your own provider.
Frequently Asked Questions
Yes. Atomoxetine and viloxazine can raise heart rate and blood pressure, so every ADHD medicine, stimulant or not, needs a heart review first.
Bupropion (Wellbutrin) is used off-label, especially when depression is also present. Guanfacine extended-release (Intuniv) and clonidine extended-release are approved for children and sometimes used in adults, alone or with a stimulant.
Atomoxetine and viloxazine carry a warning about suicidal thoughts in younger patients. Report any worsening mood promptly. If you are in crisis, call or text 988.