How bupropion affects attention, what the evidence shows for adult ADHD, who it suits, who should avoid it, and its common side effects.
Looking for a Primary Care Provider?
Checkups, preventive care and ongoing care for chronic conditions in West Ashley, Charleston. New patients are often able to be scheduled within a week of requesting an appointment. Schedule an appointment today.
In this guide
It May Suit Adults Who
- Have ADHD and depression
- Want to quit smoking
- Prefer to avoid stimulants
It Is Not for People With
- A seizure disorder
- Bulimia or anorexia
- An abrupt stop of alcohol or sedatives
Common Side Effects
- Insomnia or dry mouth
- Headache or jitteriness
- Lower appetite
What the guideline says
- Bupropion (Wellbutrin) is an antidepressant that affects dopamine and norepinephrine, two brain chemicals involved in attention.
- Bupropion is not FDA-approved for ADHD, but it is sometimes used off-label for adults, especially when depression is also present.
- Studies show a modest benefit for adult ADHD symptoms, smaller than with stimulants.
- It may suit adults with ADHD and depression, adults who want to quit smoking, adults who cannot take or prefer to avoid stimulants, and adults bothered by sexual side effects from SSRIs.
- People with a seizure disorder or an eating disorder, or who are stopping alcohol or sedatives abruptly, should avoid it because bupropion lowers the seizure threshold.
Source: MedlinePlus, Bupropion
Read the full article: Wellbutrin for ADHD: When Bupropion Makes Sense for Adults →
This guide is general health information and does not replace advice from your own provider.
Frequently Asked Questions
Insomnia, dry mouth, headache, jitteriness and lower appetite are common.
Bupropion lowers the seizure threshold. That is why people with a seizure disorder, an eating disorder such as bulimia or anorexia, or who are stopping alcohol or sedatives abruptly should avoid it.
Talk with your provider first. They can review your other medicines and conditions, and talk through whether bupropion fits, especially if you have ADHD and depression.